Antiseizure Medications Induce Drug-Specific Shifts in the Aperiodic Exponent of Chronic Ambulatory Intracranial Electrocorticography (Neuroscience 2026) - Sep 27, 2026 - Abstract #NANO32.04; Pres time: Nov 17, 2026; 01:45 PM - 02:00 PM; Location: WCC Rm 207A; "Pre- and post-medication periods (±60 days) were compared for 7 newly initiated ASMs (cenobamate, brivaracetam, clobazam, cannabidiol, clonazepam, gabapentin, and levetiracetam). The aperiodic exponent may serve as a within-individual indicator of ASM-induced E/I perturbation. Limitations include small per-drug samples (N = 5-16), co-titration, dose heterogeneity, and observational design."
CNS Disorders • Epilepsy
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F. TU1; S. SMITH2; T. YADAV1; I. H. QURAISHI1
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