vanzacaftor (VX-121) - Vertex
elexacaftor (VX-445) - Vertex
Trikafta (elexacaftor/tezacaftor/ivacaftor) - Vertex
Alyftrek (vanzacaftor/tezacaftor/deutivacaftor) - Vertex
Kalydeco (ivacaftor) - Vertex
The New Landscape of Cystic Fibrosis in the Era of Highly Effective Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy. (PubMed, J Mother Child) - Sep 26, 2026 - "As patient life expectancy continues to increase, comorbidities such as arterial hypertension, hypercholesterolaemia, cardiovascular disease, and malignancies will assume greater clinical importance. Selecting optimal therapeutic strategies remains a significant clinical challenge due to the numerous potential interactions between modulators and other medications." 
Journal • Review • Cardiovascular • Cystic Fibrosis • Dyslipidemia • Genetic Disorders • Hypertension • Immunology • Oncology • Pulmonary Arterial Hypertension • Pulmonary Disease • Respiratory Diseases • CFTR
http://www.ncbi.nlm.nih.gov/pubmed/42790887
 
Dorota Sands; Justyna Milczewska; Katarzyna Walicka-Serzysko
 
Sep 26, 2026
 
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