Orkambi (lumacaftor/ivacaftor) - Vertex
Symdeko (tezacaftor/ivacaftor) - Vertex
Changes in Inhaled Antibiotic Associated lung function outcomes in the CFTR-Modulator Era. (PubMed, Chest) - Sep 22, 2026 - "The risk of treatment emergent infections was highest in Pa negative pwCF who conversely did not have antibiotic-associated benefit on lung function. For pwCF with chronic Pa the antibiotic-associated benefit decreased as CFTR-modulator use increased." 
Journal • Cystic Fibrosis • Genetic Disorders • Immunology • Infectious Disease • Pulmonary Disease • Respiratory Diseases
http://www.ncbi.nlm.nih.gov/pubmed/42767597
 
Jane She; John J LiPuma; Marianne S Muhlebach; Michael R Kosorok
 
Sep 22, 2026
 
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