Validation of a Method for Quantifying Elexacaftor, Elexacaftor-M23, Tezacaftor, Tezacaftor-M1, and Ivacaftor by HPLC-PDA. (PubMed, Drug Metab Bioanal) - Sep 21, 2026 - "The method is fast, reproducible, and suitable for the simultaneous quantification of CFTR modulators and their main metabolites in plasma. It is applicable in clinical laboratories for the therapeutic monitoring and optimization of cystic fibrosis pharmacotherapy."
Journal • Cystic Fibrosis • Genetic Disorders • Immunology • Pulmonary Disease • Respiratory Diseases • CFTR
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Adriana H Sassone; Alejo G Dominas; Andrea S Saulo; Claudio Castaños; Mario Sakson; Paulo Cáceres Guido
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