Optimized Ultrasound-Assisted Extraction Enhances the Recovery of Anti-Collagenase Phytochemicals from Mitragyna speciosa Korth. Leaves. (PubMed, Plants (Basel)) - Aug 28, 2026 - "Molecular docking identified chlorogenic acid as the strongest predicted collagenase binder (-12.82 kcal/mol), though chlorogenic acid and rutin together could not fully account for the extract's activity, suggesting possible contributions from K3G and other unidentified compounds. These findings provide preliminary evidence for the cosmeceutical potential of kratom leaf extract, pending control of its alkaloid content."
Journal • Pain
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Mathukorn Sainakham; Nara Yaowiwat; Pimporn Leelapornpisid; Siripat Chaichit; Thasang Thavanapong; Worrapan Poomanee
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