Eucommia ulmoides Bark Extract Attenuates Oxidative Damage and H2O2-Induced Hair Follicle Suppression in Cellular and Mouse Models. (PubMed, Molecules) - Aug 28, 2026 - "This study evaluated the antioxidant, follicle-supporting, and antiandrogenic potential of Eucommia ulmoides bark extract (EUE) using integrated in vitro and in vivo approaches and characterized EUE by HPLC-DAD using geniposidic acid and chlorogenic acid as representative marker compounds...In male C57BL/6 mice, topical EUE attenuated H2O2-induced suppression of hair follicle elongation and improved follicular morphology. Overall, EUE is a chemically characterized botanical extract with preliminary biological activities relevant to oxidative stress- and androgen-associated hair disorders; independent replication, active-compound identification, marker-specific permeation, and protein-level validation of the measured markers remain necessary."
Journal • Preclinical • Melanoma • Oncology • Solid Tumor • CTNNB1
|
|
Shuyue Chen; Xiaojin Liu; Yanyan Zhang; Yaqian Qiu; Yefan Gu
|