Ruanjian Sanjie Formula Affects Metastasis of Lung Cancer by Regulating miR-182-5p/EPAS1/EMT Axis. (PubMed, Chin J Integr Med) - Aug 16, 2026 - "RJSJ inhibits lung cancer occurrence and metastasis both in vivo and in vitro. Mechanistically, RJSJ suppresses the EMT process by downregulating miR-182-5p and inhibiting EPAS1 expression, thereby restraining lung cancer malignant progression, with chlorogenic acid identified as a key active component."
Journal • Lung Cancer • Oncology • Solid Tumor • CDH1 • CDH2 • EPAS1 • MIR182 • MMP2 • MMP9
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Guan-Jin Wu; Jia-Lin Yao; Li-Jing Jiao; Ling Bi; Ling Xu; Qin Wang; Wen-Xiao Yang; Xu Wang; Yi-Nan Yin; Zong-Mei Zheng
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