Characterization of Spent Coffee Grounds' Polyphenol Fraction and Its Potential as a Low-Cost Tool for Bioactivity-Guided Nephroprotective Modulation of Gut-Kidney Axis and NF-κB/Nrf2/TGF-β Signaling in Hypertension-Associated Kidney Injury. (PubMed, Antioxidants (Basel)) - Jul 29, 2026 - "SCG polyphenol fraction shows strong nephroprotective potential via gut-kidney axis modulation and NF-κB/Nrf2/TGF-β regulation, supporting its development as a low-cost therapeutic candidate."
Journal • Cardiovascular • Fibrosis • Hypertension • Immunology • Inflammation • Renal Disease • KEAP1 • TGFB1
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Antonello Santini; Danny Pratama Kuswadi; Dante Saksono Harbuwono; Edwin Hadinata; Eka Ginanjar; Fahrul Nurkolis; Lucia De Luca; Metalia Puspitasari; Pringgodigdo Nugroho; Raffaele Romano; Raymond Rubianto Tjandrawinata; Siti Nur Rohmah; Yulia Wardhani
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