Spectrum-effect relationship and network pharmacology reveal key anti-rheumatoid arthritis and attenuated toxicity components of processed Curculigo rhizome. (PubMed, J Ethnopharmacol) - Jul 28, 2026 - "This study provides scientific evidence supporting the traditional wine-processing method for CR and demonstrates that WCR maintains equivalent anti-RA efficacy with improved safety compared to RCR. The identified bioactive components and the glycolysis-inhibitory mechanism offer novel insights for quality control standardization and therapeutic development of CR-based interventions for rheumatoid arthritis."
Journal • Immunology • Inflammation • Inflammatory Arthritis • Rheumatoid Arthritis • Rheumatology • CASP3 • EGFR • GAPDH • IL1B • PFKFB3 • PKM • SLC2A1 • TNFA
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Fei Li; Jia-Lin Yu; Meng-Hua Pan; Shu-Fan Liu; Yong-Jian Ai
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