Pimpinella brachycarpa extract attenuates periodontal inflammation by modulating the PI3K/Akt-NF-κB signaling pathway. (PubMed, Front Pharmacol) - Oct 15, 2026 - "Chemical profiling identified chlorogenic acid, luteolin 7-O-glucuronide, apigenin 7-O-glucuronide, and luteolin 3'-O-glucuronide as major constituents...In addition, flavonoid glucuronides identified in PBE exhibited anti-inflammatory activities in vitro. Further studies are required to clarify the contribution of individual constituents to the biological activity of PBE." Journal • Dental Disorders • Inflammation • Osteoporosis • Periodontitis • IL1B • IL6 • MMP13 • MMP3 • NFKBIA • TNFA
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A Yeong Lee; Dong-Seon Kim; Eunjung Son; Hyeri Ku; Jung-In Kim; Junghyun Kim; Soon Yeong Park; Su-Bin Park; Yun Mi Lee
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