Polyphenol-Rich Oenanthe javanica as a Cardioprotective Functional Food Candidate Exhibiting Antiplatelet Activity via Suppression of Ca2+ Mobilization and Thromboxane A2 Production. (PubMed, Int J Mol Sci) - Jun 27, 2026 - "Aggregation, Fura-2 [Ca2+]i, and TXB2 were measured, including combinations with verapamil, aspirin, caffeic acid (CA), and chlorogenic acid (CGA). Dietary OJWE modestly but significantly reduced rat platelet aggregation without altering coagulation. OJWE attenuates platelet activation by selectively targeting Ca2+ mobilization and TXA2 biosynthesis without compromising hemostasis, supporting O. javanica as a functional food with cardiovascular potential at dietary intake."
Journal • Cardiovascular
|
|
Hwa-Jin Park; Hyeonha Jang; Jae-Ho Shin; Jeong-Soo Bae; Min-Kyu Park; Sung-Hun Choi
|