MYB73 modulates apple flesh browning by repressing the expression of three polyphenol oxidase genes. (PubMed, Plant Physiol) - Jun 19, 2026 - "By measuring PPO activities and phenolic concentrations, we found that while slightly elevated concentrations of chlorogenic acid and catechin may contribute to enhanced flesh browning in cMa1-OE fruit at the early stages of fruit development, increased flesh browning at harvest is primarily caused by up-regulated PPO activities...RNAi suppression of MdMYB73 increased MdPPO3, MdPPO15, and MdPPO16 expression and total PPO activity, leading to enhanced flesh browning; however, this effect was blocked by RNAi of MdPPO3/MdPPO15/MdPPO16. These results indicate that MdMYB73 regulates apple flesh browning via suppressing MdPPO3, MdPPO15, and MdPPO16 expression; overexpression of Ma1 decreases MdMYB73 expression in fruit, which releases the suppression of the MdPPO genes, leading to enhanced flesh browning." Journal
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Ewa Borejsza-Wysocka; Lailiang Cheng; Mengxia Zhang; Nan Wang
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