Anticancer activity and molecular docking of active ingredients from ethanolic extract of grapefruit peels against HepG2 cell. (PubMed, Sci Rep) - Jun 11, 2026 - "Results Phytochemical screening revealed high phenolic and flavonoid content, with naringenin being the most abundant compound, followed by chlorogenic acid and ferulic acid...Interaction analysis revealed multiple hydrogen bonding and π-interactions with key AFP residues, including LYS228, CYS224, PHE172, GLU489, and MET490...Despite its lower potency compared to doxorubicin, it represents a valuable natural source of bioactive compounds. Further studies are required to elucidate its mechanisms, safety, and potential application in hepatocellular carcinoma therapy."
Journal • Hepatocellular Cancer • Oncology • Solid Tumor
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Ahmed M Aboul-Enein; Clara R Azzam; Emad A Shalaby; Mariam M Soliman; Nourhan A Aboelnaga; Soha S Mostafa
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