Red Grape Pomace as a Valuable Source of Biomolecules With Inhibitory Effect on Pro-Inflammatory and Metabolic Syndrome-Associated Enzymes: Eco-Friendly Extraction and Mechanism of Inhibition. (PubMed, Food Sci Nutr) - Jun 9, 2026 - "The main identified compounds were vanillic acid, azelaic acid, chlorogenic acid, suberic acid, abietic acid, phlorizin, polydatin, and t-resveratrol...Different phenolic compounds were identified to attach to the active site of the enzymes, interfering with their activity. The anti-diabetic activity might be assigned to vanillic acid and suberic acid, which bind to α-amylase and α-glucosidase respectively, whereas suberic acid and resveratrol appeared to be responsible for the direct inhibitory mechanism of lipoxygenase."
Journal • Metabolic Disorders
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Elisabeta Irina Geana; Gabriela Râpeanu; Ilir Mërtiri; Iuliana Aprodu; Nicoleta Balan
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