Phytochemical Characterization and Antipyretic and Antinociceptive Activities of Echinops orientalis Trautv. Methanolic Flower Extract: Evidence from In vivo Studies, Network Pharmacology and Molecular Docking. (PubMed, J Ethnopharmacol) - Sep 26, 2026 - "Echinops orientalis MFE shows antipyretic and antinociceptive potential, supporting its traditional use. Computational predictions suggest modulation of cyclooxygenase (COX-2), prostaglandin E2 receptor (EP2), thromboxane synthase (TBXAS1) and interconnected inflammatory pathways, a hypothesis requiring experimental validation and further preclinical investigation."
Journal • Preclinical • Pain • AKT1 • EGFR • IL6 • STAT3
|
|
Bushra Hassan Marouf; Hastyar Hama Rashid Najmuldeen; Karmand Salih Hamaamin; Mohammed Koksh Sidiq; Pshtiwan Ghareb Ali; Sakar Yassin Hama Rahim; Saman Abdulrahman Ahmad; Sara Fayaq Fariq; Sima Rahman Qadir; Twana Mohsin Salih; Zhawen Noori Hussein
|