Eriobotrya japonica (Loquat) Leaf Extract: An Integral In Vitro and In Ovo Approach to Antimelanoma Potential and Safety. (PubMed, Int J Mol Sci) - Sep 16, 2026 - "The most abundant compounds in the extract were chlorogenic acid, rutin, 3,5-dihydroxybenzoic acid/3,4-dihydroxybenzoic acid, and p-coumaric acid/trans-p-coumaric acid...The HET-CAM assay classified the extract as non-irritant at 500 µg/mL. These findings suggest that Eriobotrya japonica leaf extract exerts antimelanoma effects associated with oxidative stress and mitochondrial dysfunction while maintaining a favorable preliminary safety profile."
Journal • Preclinical • Melanoma • Metabolic Disorders • Oncology • Solid Tumor
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Alex-Robert Jîjie; Alina Anton; Andreea Maria Cristea; Cristina Adriana Dehelean; Diana Haj Ali; Diana-Simona Tchiakpe-Antal; Dorina Elena Coricovac; Mihaela L?c?tu?; Raluca Andreea Jupânean?
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