Untargeted Metabolomic and Phytochemical Profiling of Berberis crataegina DC. Plant Parts: Antidiabetic Potential and Cytoprotection in High-Glucose-Exposed SH-SY5Y Cells. (PubMed, Pharmaceuticals (Basel)) - Sep 27, 2026 - "Chlorogenic acid, rutin, caffeic acid, protocatechuic acid, quercetin, and quercetin-3-O-glucoside were detected and quantified in the fruit extract by HPLC-DAD...The findings suggest that these effects may arise from the combined contribution of multiple constituents within a polyphenolic matrix rather than from a single compound; however, synergistic interactions were not experimentally demonstrated. These results support further evaluation of the fruit extract through mechanistic, in vivo, and standardization studies."
Journal • Diabetes • Diabetic Neuropathy • Pain
|
|
Emirhan Nemutlu; Engin Koçak; Merve Yüzba??o?lu Baran; Yi?it Erkmen; Zekiye Ceren Ar?tuluk Ayd?n
|