Disease-specific and therapy-driven alterations in immunoglobulin G heavy-chain repertoire in peripheral blood mononuclear cells from pemphigus vulgaris and bullous pemphigoid patients. (PubMed, Mol Immunol) - Oct 14, 2026 - "PV and BP patients exhibited disease-specific IGHG repertoire alterations. GC-RTX therapy has stronger effects than GC monotherapy, leading to more pronounced IGHG repertoire remodeling. This study offers valuable insights for both immunopharmacological investigations and immunotherapy development in autoimmune bullous disorders."
Journal • Bullous Pemphigoid • Dermatology • Dermatopathology • Immunology • Pemphigus Vulgaris
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Delong Feng; Guiying Zhang; Ming Zhao; Qian Wang; Wenyu Zhou; Zhi Hu
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