Combined Exendin-4 and Rituximab Treatment Improves β-Cell Function and Delays Disease Progression in NOD Mice. (PubMed, Biology (Basel)) - Sep 16, 2026 - "Histological and molecular analyses further demonstrated reduced pancreatic inflammatory damage, reduced apoptosis-associated changes, and increased BrdU- and cytokeratin-18-associated signals within insulin-positive islet regions. These findings support further investigation of combined B-cell-directed and β-cell-supportive strategies for preserving islet function and delaying disease progression in type 1 diabetes."
Journal • Preclinical • Diabetes • Metabolic Disorders • Type 1 Diabetes Mellitus • KRT18
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Baicheng Ma; Huan Yang; Jianjun Xiong; Jiashuo Qiu; Jie Zhang; Likun Yu; Shan He; Xingnuan Li; Yongbin Wang
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