From Rescue Therapy to Mechanism-Based Sequencing in Refractory Myasthenia Gravis: A Narrative Review with an Illustrative Clinical Case. (PubMed, J Clin Med) - Oct 17, 2026 - "An illustrative case of severe refractory AChR-Ab-positive gMG showed incomplete control after conventional immunosuppression, rituximab, thymectomy, and terminal complement inhibition, with reproducible but transient benefit from plasma exchange...Mechanism-based sequencing should be viewed as structured decision support rather than a validated algorithm. Prospective switching studies and predictive biomarkers are needed to optimize individualized treatment sequencing."
Journal • Review • CNS Disorders • Immunology • Myasthenia Gravis
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Aleksandr Ilves; Vera Nikitin
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