Prostatic Involvement in Granulomatosis with Polyangiitis: A Case Report and Scoping Review. (PubMed, Diagnostics (Basel)) - Oct 17, 2026 - "With concurrent sinonasal and mastoid disease, karyorrhectic necrosis on histology, and low-titre ANCA positivity, GPA was diagnosed and treated with glucocorticoids and cyclophosphamide followed by rituximab, with regression of active disease but persistent structural sequelae. Prostatic involvement may extend contiguously into the urethra, bladder, penile structures and upper urinary tract; the present case is one of the most extensive examples identified in this review. Sterile, antibiotic-refractory urogenital lesions, especially with extra-urogenital disease, low-titre or discordant ANCA serology, should prompt consideration of GPA before irreversible anatomical loss."
Journal • ANCA Vasculitis • Infectious Disease • Oncology • Rare Diseases • Vasculitis
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Jakub Kulski; Kevin Miszewski; Laura Miszewska; Marcin Matuszewski; Oliwia Ka?wak
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