LUCID: Fully Automated nnU-Net-Based Total Tumor Volume Segmentation in Longitudinal SPECT/CT for Radiopharmaceutical Therapy (EANM 2026) - Sep 29, 2026 - Abstract #OP-161; Pres time: Oct 18, 2026; 03:00 PM - 04:30 PM; Location: Hall B; P2 | "Materials and This study included post-therapy quantitative SPECT/CT scans from patients treated with ¹⁷⁷Lu-PSMA-617 in the PR21 trial (NCT04663997, n=39) and ¹⁷⁷Lu-HTK03170 (NCT0557099, n=6), with multiple scans available across treatment cycles... We present LUCID, a fully automated nnU-Net-based framework for whole-body tumor segmentation and TTV quantification in post-therapy SPECT/CT for RPTs. While downstream review remains part of the current workflow, LUCID demonstrates the feasibility of automated whole-body tumor mask and TTV extraction from post-therapy SPECT/CT, providing a scalable foundation for further refinement and clinical validation."
Oncology
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R. Hamidpour Badoe 1, 2; F. Yousefirizi 1, 2; S. Kurkowska 2, 3; N. Colpo 4; C. Williams 4; C. Dellar 5; W. Parulekar 5; D. Juneau 6; F. Saad 6; K. Chi 7; K. Zukotynski 8; J. Beauregard 9, 10; M. Soleimani 11; D. Wilson 4; A. Rahmim 1, 2; F. Benard 2, 4, 1; C. Uribe 1, 2, 4
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