Clinical Feasibility of TTV Quantification on PSMA PET/CT and SPECT/CT Leveraging Deep-learning Auto-segmentation of CT Organs (EANM 2026) - Sep 29, 2026 - Abstract #OP-160; Pres time: Oct 18, 2026; 03:00 PM - 04:30 PM; Location: Hall B; "Materials and 334 PET/CT (68Ga-PSMA-11, 18F-DCFPyL) images from 12 institutions representing three camera manufacturers and 101 SPECT/CT (177Lu-PSMA-617) images from two institutions representing two camera manufacturers, were tested... The tool demonstrated good agreement with physician-generated volumes on PSMA PET and SPECT with no user edits. The marked increase in performance from 76.4% to 96% on PET and 92.1% to 100% on SPECT with 3 or fewer user edits supports its feasibility for standardized and efficient total tumor volume quantification in routine clinical practice. In line with our findings, Emmett et al." Clinical • Castration-Resistant Prostate Cancer • Genito-urinary Cancer • Prostate Cancer • Solid Tumor
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K. Ngai; A. S. Nelson; N. Dwivedi
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