Single-Time-Point Time-Integrated Activity Estimation in 177 Lu-PSMA Therapy: Evaluation of Analytical and Hybrid Machine Learning Methods (EANM 2026) - Sep 29, 2026 - Abstract #EP-1262; "Materials and A retrospective cohort of 34 patients with mCRPC treated with 177Lu-PSMA-617 was analyzed in the first treatment cycle... Analytical STP methods provide accurate TIA estimates when applied at appropriate imaging times. Hybrid ML approaches reduce bias in STP TIA estimates in some settings, while achieving performance comparable to analytical methods in optimal TPs. Further gains may be achievable with larger and more diverse datasets."
Machine learning • Castration-Resistant Prostate Cancer • Prostate Cancer
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Z. Mansouri 1; K. Fitzpatrick 2; M. Fredericks 2; K. Suresh 3; M. Roseland 2; K. Wong 2; H. Zaidi 1; Y. K. Dewaraja 2
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