Augmented Reduced-Intensity Regimen with Cyclophosphamide in Acute Myeloid Leukemia Patients (ICBMT 2025) - Sep 15, 2025 - Abstract #PP02-05; "All patients received a reduced-intensity conditioning regimen consisting of fludarabine (30 mg/m²/day for 5 days), busulfan (3.2 mg/kg/day for 2 days), and cyclophosphamide (60 mg/kg for 1 day), followed by infusion of hematopoietic stem cells. Augmented cyclophosphamide in a RIC regimen was well tolerated and associated with rapid engraftment. GVHD rates were higher than in earlier reports. Patients treated in 2020–2024 showed significantly improved OS and a trend toward better DFS."
Clinical • Acute Graft versus Host Disease • Acute Myelogenous Leukemia • Bone Marrow Transplantation • Chronic Graft versus Host Disease • Graft versus Host Disease • Hematological Malignancies • Immunology • Leukemia
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Sao-Chih Ni 1; Feng-Ming Tien 2; Xavier Cheng-Hong Tsai 2; Chien-Chin Lin 3; Jia-Hau Liu 1; Chi-Cheng Li 5; Hsin-An Hou 1; Sheng-Yi Huang 1; Wen-Chien Chou 1, 3; Ming Yao 1; Jih-Luh Tang 1, 4; Bor-Sheng Ko 1, 2
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