PUM1 enhances PAK6 mRNA stability and contributes to growth and ferroptosis resistance in lung adenocarcinoma cells.

erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys

PUM1 enhances PAK6 mRNA stability and contributes to growth and ferroptosis resistance in lung adenocarcinoma cells. (PubMed, Pathol Res Pract) - Jul 23, 2025 - "This study demonstrates that PUM1 enhances the RNA stability of PAK6, thereby contributing to ferroptosis resistance in LUAD cells."
Journal • Lung Adenocarcinoma • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • CDKN1A • PAK1 • PAK6 • PUM1 • RAC1

http://www.ncbi.nlm.nih.gov/pubmed/40694989

Haixia Wang; Jing Zhang; Xiangyu Su; Xin Shi; Xuejun He; Yang Li

Jul 23, 2025