Melatonin Attenuates Spinal Cord Injury by Regulating Ferroptosis Through the Nrf2/HO-1/GPX4 Pathway. (PubMed, Mol Neurobiol) - Jul 20, 2025 - "A ferroptosis model directly induced by Erastin was also used...ML385, an Nrf2 inhibitor, reversed the effects of MT. Overall, MT may alleviate early SCI by inhibiting ferroptosis through activating the Nrf2/heme oxygenase-1(HO-1)/glutathione peroxidase 4 (GPX 4) pathway."
Journal • Cardiovascular • CNS Disorders • Orthopedics • Reperfusion Injury • GPX4 • HMOX1
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Dehui Chen; Dingwei Wu; Hailin Lin; Hao Feng; Huina Chen; Lei Sun; Tengbin Shi; Wenge Liu; Zhengxi Yu
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