erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys
LINC02266 promotes proliferation and metastasis and inhibits ferroptosis of gastric cancer cells by regulating AKT/ACSL4 pathway. (PubMed, Mol Cell Biochem) - Jul 20, 2025 - "Mechanistically, we found that LINC02266 inhibited erastin-induced ferroptosis by suppressing ACSL4 levels, which may be related to the AKT pathway. This study indicates that LINC02266 can serve as a diagnostic marker and novel therapeutic target for GC." 
Journal • Gastric Cancer • Oncology • Solid Tumor • ACSL4
http://www.ncbi.nlm.nih.gov/pubmed/40682711
 
Chang Liu; Feng Chen; Lijie Zhang; Xiaomin Zhao; Xiaoru Liang; Xinyu Niu; Zhijuan Lin
 
Jul 20, 2025
 
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