l-Theanine Improves Learning and Memory Through Attenuation of NOX4-Mediated Ferroptosis in Hippocampal Neurons of Sleep-Deprived Mice. (PubMed, Phytother Res) - Jul 19, 2025 - "Furthermore, l-theanine mitigated Erastin-induced oxidative stress and ferroptosis in HT22 cells...Moreover, the neuroprotection of l-theanine was reversed by the GLX351322 agent. l-Theanine treatment inhibited hippocampal ferroptosis by attenuating NOX4, suggesting that it can be used to mitigate the adverse effects of SD."
Journal • Preclinical • ACSL4 • GPX4 • KEAP1 • NOX4 • NQO1 • SLC7A11
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Hongfei Wu; Xinglong Lu; Xuanxuan Huang; Yin Cao; Zhenghua Wu; Zhongwen Xie
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