Deciphering the Role of Ferroptosis in the Pathogenesis of Peripheral Artery Disease Myopathy. (PubMed, Biology (Basel)) - May 28, 2025 - "Cultured myotubes treated with the ferroptosis inducer erastin provided an in vitro comparison...Protein analysis showed trends consistent with gene expression in some ferroptosis markers. The increase in ferroptosis markers in CLI PAD patients, particularly in iron metabolism and autophagy pathways, suggests ferroptosis contributes to PAD myopathy."
Journal • Atherosclerosis • Cardiovascular • Muscular Atrophy • Myositis • Peripheral Arterial Disease • ACSL4 • BECN1 • ELAVL1 • HMOX1 • PACERR • PTGS2
|
|
Andrew Ring; Cassandra Bradley; Dimitrios Miserlis; Emma Fletcher; Evlampia Papoutsi; Iraklis I Pipinos; Panagiotis Koutakis; Robert S Smith; Trevor Wilkinson; William T Bohannon
|