erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys
PRDX1 knockdown promotes erastin-induced ferroptosis and impedes diffuse large B-cell lymphoma development by inhibiting the MAPK/ERK pathway. (PubMed, BMC Cancer) - May 1, 2025 - "PRDX1 knockdown facilitates erastin-induced ferroptosis and obstacles DLBCL progression by inhibiting the MAPK/ERK pathway, offering a potential treatment strategy for DLBCL treatment." 
Journal • B Cell Lymphoma • Diffuse Large B Cell Lymphoma • Hematological Malignancies • Lymphoma • Non-Hodgkin's Lymphoma • Oncology • GPX4 • MT-CO2 • PRDX1 • SLC7A11
http://www.ncbi.nlm.nih.gov/pubmed/40307771
 
Chuanming Lin; Jianzhen Shen; Menger Wang; Shuiling Xie
 
May 1, 2025
 
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