The role of ferroptosis as a novel alternative cell death model in thyrocytes from Hashimoto´s thyroiditis patients (ESPE-ESE 2025) - Apr 5, 2025 - Abstract #RC11.4; Pres time: May 12, 2025; 02:50 PM - 02:55 PM; Location: Auditorium 15; "Methodology: we analyzed lipid peroxidation with a sensor for lipid peroxidation (BodipyTM 581/591 C11) in a human thyroid follicular cell line stimulated with HT-associated proinflammatory cytokines (IFN-γ and TNF-α), ferroptosis inductors (RSL3 and erastin) and inhibitors (ferrostatin-1). our data indicates that ferroptosis may constitute a novel alternative cell death model in HT pathogenesis because of the proinflammatory microenvironment."
Clinical • Addiction (Opioid and Alcohol) • Endocrine Disorders • Grave's Disease • Immunology • GPX4 • IFNG • TNFA
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Pablo Sacristán-Gómez * 1; Susana Delgado-Martín 2; Ana Serrano-Somavilla 1; Nuria Sánchez de la Blanca Carrero 1; Andrea Álvarez-Rodríguez 1; Jose Luis Muñoz de Nova 3; Miguel Antonio Sampedro-Nuñez 1; Antonio Martínez-Ruiz 2; Monica Marazuela 1; Rebeca Martínez-Hernández 1
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