A novel way of regression of pregnant corpus luteum during parturition in mice: The ferroptosis associated with NCOA4-mediated ferritinophagy. (PubMed, Biochem Pharmacol) - Apr 3, 2025 - "Erastin (ferroptosis agonist) treatment significantly accelerated luteal regression and induced premature labor in pregnant mice...In summary, our current data demonstrated that the ferroptosis associated with NCOA4-mediated ferritinophagy was a novel way of luteal regression during peri-parturition in mice. Targeting ferroptosis in the corpus luteum may be a therapeutic strategy for preventing luteal insufficiency in the future."
Journal • Preclinical • NCOA4
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Bei Yang; Fei Li; Haibin Kuang; Hongru Zhao; Jiahao Song; Jiting Yin; Jun Zhu; Yanmin Cheng; Yue Li; Yulu Zhang
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