α-Hederin causes ferroptosis in triple-negative breast cancer through modulating IRF1 to suppress GPX4. (PubMed, Phytomedicine) - Mar 29, 2025 - "We proved for the first time in this research that α-Hederin exerts anti-TNBC effects through a novel IRF1/GPX4 ferroptosis pathway."
Journal • Breast Cancer • Oncology • Solid Tumor • Triple Negative Breast Cancer • GPX4 • IRF1
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Chaoyue Lv; Disuo Ren; Erjie Xia; Heyu Zhang; Jiatong Ru; Jingxia Bao; Lingli Jin; Ouchen Wang; Shaolong Huang; Shuwei Zhang; Xinyu Meng; Xue Wu; Zhixuan Wu
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