Morroniside alleviates cisplatin-induced renal injury and gut dysbiosis via the gut-kidney axis and ferroptosis. (PubMed, Int Immunopharmacol) - Mar 19, 2025 - "Morroniside mitigated cisplatin-induced renal injury by inhibiting ferroptosis through the GPX4/p53 pathway, reducing oxidative stress via Nrf2/HO-1 axis, and improving gut microbiota dysbiosis, indicating its potential in mitigating cisplatin-induced renal injury."
Journal • Nephrology • Oncology • Renal Disease • GPX4 • HMOX1
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Bojian Yu; Fangfang Huang; Hangting Li; Ke Xu; Wenhao Mao; Zhongliang Liu; Zuisu Yang
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