Research progress on ferroptosis in head and neck squamous cell carcinoma. (PubMed, J Mol Histol) - Mar 17, 2025 - "Therapeutic exploration has identified ferroptosis inducers (e.g., erastin) as promising agents to disrupt redox equilibrium in HNSCC cells, while pharmacological inhibitors offer potential for mitigating off-target toxicity...This study aims to provide a mechanistic framework for ferroptosis in HNSCC, bridging preclinical insights with translational opportunities. By elucidating context-dependent regulatory networks and optimizing therapeutic targeting, we propose novel strategies to overcome treatment resistance, ultimately improving clinical outcomes and quality of life for HNSCC patients."
Journal • Review • Head and Neck Cancer • Metabolic Disorders • Oncology • Solid Tumor • Squamous Cell Carcinoma • Squamous Cell Carcinoma of Head and Neck • SLC7A11
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Guijuan Feng; Wenli Sai; Yi Qiu; Yuyuan Su
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