Illumination of Hydroxyl Radical Generated in Cells during Ferroptosis, Arabidopsis thaliana, and Mice Using a New Turn-On Near-Infrared Fluorescence Probe. (PubMed, Anal Chem) - Dec 14, 2024 - "More importantly, Probe-HMP can achieve the detection of endogenous ·OH in HepG2 cells during ferroptosis by using erastin and deferoxamine mesylate (DFO) to induce or inhibit ferroptosis, revealing that the fluorescence intensity change of Probe-HMP was caused by ·OH generated and ferroptosis is accompanied by significant ·OH generation. The excellent performance of Probe-HMP makes it a promising candidate for exploring the physiological and pathological processes associated with ferroptosis."
Journal • Preclinical
|
|
Changying Song; Chengxiao Zhang; Dongli Jia; Haiyang Ji; Honglan Qi; Hongyu Ma; Qiuyue Wang; Yitong Hao; Zhao Li
|