Temperature-Responsive Hydrogel System Integrating Wound Temperature Monitoring and On-demand Drug Release for Sequentially Inflammatory Process Regulation of Wound Healing. (PubMed, ACS Appl Mater Interfaces) - Nov 26, 2024 - "Furthermore, photothermally responsive and erastin-loaded polydopamine@PNIPAM nanoparticles (E-PD NPs) are incorporated to release the anti-inflammatory drug erastin upon near-infrared light exposure, terminating inflammation through cytosolic burial, and thus achieve anti-inflammatory effects at the second stage of wound healing. Furthermore, a bluetooth module enables real-time wound temperature monitoring. Combining sequential drug release with temperature monitoring, our hydrogel dressing addresses significant gaps in current wound healing technologies and offers new insights into personalized therapeutic interventions."
Journal • Infectious Disease • Inflammation • CXCL8
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Borui Su; Chengheng Wu; Dan Wei; Hongrong Luo; Hongsong Fan; Ji Jiang; Jie Ding; Jing Sun; Mingze Zeng; Yuan Tian
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