Rehmanniae Radix Praeparata aqueous extract improves hepatic ischemia/reperfusion injury by restoring intracellular iron homeostasis. (PubMed, Chin J Nat Med) - Sep 27, 2024 - "In this study, we developed a HIRI mouse model and monocrotaline (MCT)- and erastin-induced in vitro hepatocyte injury models...In conclusion, our study elucidates the mechanisms by which RRP aqueous extracts alleviate HIRI, highlighting the restoration of iron metabolic balance. These findings position RRP as a promising candidate for clinical intervention in HIRI treatment."
Journal • Cardiovascular • Reperfusion Injury • Transplantation • CISD1
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Fanghong Li; Guifang Fan; Jia Liu; Kexin Jia; Ranyi Luo; Runping Liu; Xiaojiaoyang Li; Yajing Li; Yang Yang; Yinhao Zhang; Yufei Li; Zhi Ma
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