tRF-Gly-GCC in Atretic Follicles Promotes Ferroptosis in Granulosa Cells by Down-Regulating MAPK1. (PubMed, Int J Mol Sci) - Sep 1, 2024 - "Healthy follicles ranging from 4 to 5 mm were randomly divided into two groups: a control group (DMSO) and treatment group (10 uM of ferroptosis inducer erastin)...tRF-1:30-Gly-GCC-2 may be a novel molecular target for improving the development of atretic follicles in ovarian dysfunction. In conclusion, our study provides a new perspective on the pathogenesis of granulosa cell dysfunction and follicular atresia."
Journal • MAPK1
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Jiang Tong; Jiaxin Li; Jinkang Feng; Lei Chen; Li Zhu; Lili Niu; Lingfan Kang; Linyuan Shen; Mailin Gan; Qian Chen; Shuang Wu; Shunhua Zhang; Yan Wang; Ye Zhao; Yuheng Pan; Yunhong Jing; Yuxu He
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