METTL3 in cancer-associated fibroblasts-derived exosomes promotes the proliferation and metastasis and suppresses ferroptosis in colorectal cancer by eliciting ACSL3 m6A modification.

erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys

METTL3 in cancer-associated fibroblasts-derived exosomes promotes the proliferation and metastasis and suppresses ferroptosis in colorectal cancer by eliciting ACSL3 m6A modification. (PubMed, Biol Direct) - Aug 20, 2024 - "CAFs promoted the proliferation and metastasis, and restrained the ferroptosis in CRC by exosomal METTL3-elicited ACSL3 m6A modification."
Journal • Colorectal Cancer • Gastrointestinal Cancer • Oncology • Solid Tumor • ACSL3 • CAFs • METTL3

http://www.ncbi.nlm.nih.gov/pubmed/39160584

Hongbing Ma; Hongtao Ren; Lei An; Mincong Wang; Xiulong Ma; Yuyan Guo

Aug 20, 2024