erastin - Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute, Columbia University, Prolexys
LncRNA FAM83H-AS1 inhibits ferroptosis of endometrial cancer by promoting DNMT1-mediated CDO1 promoter hypermethylation. (PubMed, J Biol Chem) - Aug 20, 2024 - "Cells were incubated with erastin (the ferroptosis activator)...CDO1 knockdown or FAM83H-AS1 overexpression promoted EC tumor growth in vivo. LncRNA FAM83H-AS1 inhibited ferroptosis in EC by recruiting DNMT1 to increase CDO1 promoter methylation level and inhibit its expression." 
Journal • Endometrial Cancer • Oncology • Solid Tumor • CDO1 • DNMT1 • FAM83H
http://www.ncbi.nlm.nih.gov/pubmed/39159808
 
Hui Ye; Mengyin Ao; Mingrong Xi; Minmin Hou; Ruiyu Wang; Xiuzhang Yu
 
Aug 20, 2024
 
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